[5326 Search Results


rabbits purina lab diet  (PMI Nutrition International LLC)
95
PMI Nutrition International LLC rabbits purina lab diet
Rabbits Purina Lab Diet, supplied by PMI Nutrition International LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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apilimod  (MedChemExpress)
94
MedChemExpress apilimod
Apilimod, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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antih3k4me1 antibodies  (Cell Signaling Technology Inc)
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Cell Signaling Technology Inc antih3k4me1 antibodies
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apilimod mesylate  (MedChemExpress)
93
MedChemExpress apilimod mesylate
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
Apilimod Mesylate, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sta 5326  (Synta Inc)
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Synta Inc sta 5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
Sta 5326, supplied by Synta Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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commercial rabbit feed lab rabbit chow hf 5326  (Purina Mills)
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Purina Mills commercial rabbit feed lab rabbit chow hf 5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
Commercial Rabbit Feed Lab Rabbit Chow Hf 5326, supplied by Purina Mills, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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5326 va computrace interface  (Metrohm AG)
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Metrohm AG 5326 va computrace interface
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
5326 Va Computrace Interface, supplied by Metrohm AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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high fiber rabbit diets no. 5326  (Purina Mills)
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Purina Mills high fiber rabbit diets no. 5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
High Fiber Rabbit Diets No. 5326, supplied by Purina Mills, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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c5ar inhibitor pmx-5326  (Neo MPS Inc)
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Neo MPS Inc c5ar inhibitor pmx-5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
C5ar Inhibitor Pmx 5326, supplied by Neo MPS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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5326 frequency meter  (Hewlett-Packard)
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Hewlett-Packard 5326 frequency meter
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
5326 Frequency Meter, supplied by Hewlett-Packard, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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purina hi fiber rabbit chow 5326  (Purina Petcare India Pvt Ltd)
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Purina Petcare India Pvt Ltd purina hi fiber rabbit chow 5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
Purina Hi Fiber Rabbit Chow 5326, supplied by Purina Petcare India Pvt Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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unpurified diet lab rabbit chow 5326  (Purina Mills)
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Purina Mills unpurified diet lab rabbit chow 5326
Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and <t>Apilimod</t> + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.
Unpurified Diet Lab Rabbit Chow 5326, supplied by Purina Mills, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and Apilimod + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.

Journal: Frontiers in Pharmacology

Article Title: IL-23 inhibitor enhances the effects of PTEN DNA-loaded lipid nanoparticles for metastatic CRPC therapy

doi: 10.3389/fphar.2024.1388613

Figure Lengend Snippet: Antitumor assays in vitro . (A) Cell viability of RM-1 cells after treatment with LNP@PTEN and Apilimod + LNP@PTEN for 24 h ( n = 3, means ± SD). ns: no significance, 2way ANOVA. (B, C) The statistical analysis of cells in nine fields of view of (B) anti-migration effects and (C) anti-invasion effects, respectively ( n = 9, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, ns: no significance, one-way ANOVA. (D) Microscope images of anti-migration effects and anti-invasion effects in each group (Apilimod: 10 nM, PTEN: 0.5 μg/mL), scale bars = 50 μm. (E) 3D tumor spheroid model. DiO-stained RM-1 cells and DiD-stained MC3T3-E1 cells. Blue fluorescence: DAPI, green fluorescence: DiO, red fluorescence: DiD, Scale bars = 100 μm. (F) The images of in vitro tumor spheroids penetration of each group were acquired by CLSM. DiO-stained LNPs (DiO: 20 μg/mL, Cy7-DNA: 0.5 μg/mL). Scale bars = 100 μm.

Article Snippet: Apilimod mesylate was purchased from MedChemExpress (United States).

Techniques: In Vitro, Migration, Microscopy, Staining, Fluorescence

In vivo study of LNPs. (A) Representative images of BmCRPC-bearing mice from each group were taken at 0–24 h after injection, with the tumor area marked by a red circle. (B) Fluorescence imaging of tumors and major organs. (C) The semiquantitative fluorescence intensity in major organs of each group ( n = 3, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, multiple t -test. (D) The in vivo study protocol of Apilimod + LNP@PTEN (PTEN DNA: 700 μg/kg, Apilimod: 10 mg/kg). (E) The five groups’ tumor volume curves ( n = 5, mean ± SD). (F) The five groups’ weight curves ( n = 5, mean ± SD). (G) Mice growth curves for body weight among the five groups ( n = 5, mean ± SD). (H) RT-qPCR results of the expression of PTEN in different treatment groups (n = 3, mean ± SD), *** p < 0.001, **** p < 0.0001, one-way ANOVA. (I) Survival curve of mice in different treatment groups ( n = 5, mean ± SD). **** p < 0.0001, ns: no significance, one-way ANOVA.

Journal: Frontiers in Pharmacology

Article Title: IL-23 inhibitor enhances the effects of PTEN DNA-loaded lipid nanoparticles for metastatic CRPC therapy

doi: 10.3389/fphar.2024.1388613

Figure Lengend Snippet: In vivo study of LNPs. (A) Representative images of BmCRPC-bearing mice from each group were taken at 0–24 h after injection, with the tumor area marked by a red circle. (B) Fluorescence imaging of tumors and major organs. (C) The semiquantitative fluorescence intensity in major organs of each group ( n = 3, mean ± SD), * p < 0.05, ** p < 0.01, *** p < 0.001, multiple t -test. (D) The in vivo study protocol of Apilimod + LNP@PTEN (PTEN DNA: 700 μg/kg, Apilimod: 10 mg/kg). (E) The five groups’ tumor volume curves ( n = 5, mean ± SD). (F) The five groups’ weight curves ( n = 5, mean ± SD). (G) Mice growth curves for body weight among the five groups ( n = 5, mean ± SD). (H) RT-qPCR results of the expression of PTEN in different treatment groups (n = 3, mean ± SD), *** p < 0.001, **** p < 0.0001, one-way ANOVA. (I) Survival curve of mice in different treatment groups ( n = 5, mean ± SD). **** p < 0.0001, ns: no significance, one-way ANOVA.

Article Snippet: Apilimod mesylate was purchased from MedChemExpress (United States).

Techniques: In Vivo, Injection, Fluorescence, Imaging, Quantitative RT-PCR, Expressing